San Antonio Missions Roster & Staff
SD Transactions
| Date | Transaction |
| 03/25/23 | San Diego Padres optioned SS Matthew Batten to El Paso Chihuahuas. |
| 03/24/23 | San Diego Padres optioned LHP Ray Kerr to El Paso Chihuahuas. |
| 03/22/23 | ACL Padres released RHP Brenden Heiss. |
| 03/22/23 | San Diego Padres optioned RHP Reiss Knehr to El Paso Chihuahuas. |
| 03/18/23 | San Antonio Missions released LHP Osvaldo Hernandez. |
| 03/18/23 | SS Luis Aviles Jr. assigned to San Antonio Missions. |
| 03/18/23 | San Diego Padres signed free agent SS Luis Aviles Jr. to a minor league contract. |
| 03/17/23 | 3B Jonny Homza retired. |
| 03/10/23 | San Diego Padres optioned LHP Tom Cosgrove to El Paso Chihuahuas. |
| 03/10/23 | San Diego Padres optioned RHP Angel Felipe to El Paso Chihuahuas. |
| 03/10/23 | San Diego Padres optioned RHP Pedro Avila to El Paso Chihuahuas. |
| 03/10/23 | San Diego Padres optioned RHP Michel Baez to El Paso Chihuahuas. |
| 03/09/23 | LHP CD Pelham assigned to El Paso Chihuahuas. |
| 03/06/23 | RHP Adam Mazur assigned to ACL Padres from Padres Organization. |
| 03/06/23 | LHP Robby Snelling assigned to ACL Padres from Padres Organization. |
| 03/01/23 | ACL Padres released RHP Miguel Rondon. |
| 03/01/23 | ACL Padres released RHP Levi Thomas. |
| 03/01/23 | ACL Padres released RHP Jeferson Garcia. |
| 03/01/23 | 2B Rougned Odor assigned to El Paso Chihuahuas. |
| 03/01/23 | Fort Wayne TinCaps released LHP Alexuan Vega. |
| 03/01/23 | Fort Wayne TinCaps released SS Olivier Basabe. |
| 03/01/23 | San Antonio Missions released C Tyler Malone. |
| 03/01/23 | San Diego Padres signed free agent 2B Rougned Odor to a minor league contract and invited him to spring training. |